1228150-07-9Relevant academic research and scientific papers
The design of efficient and selective routes to a key 1,4-cis-substituted cyclohexylamide intermediate
Barfoot, Christopher,Brooks, Gerald,Davies, David T.,Elder, John,Giordano, Ilaria,Hennessy, Alan,Jones, Graham,Markwell, Roger,McGuire, Michael,Miles, Timothy,Pearson, Neil,Spoors, Grant,Sudini, Ravinder,Wei, Hengxu,Wood, Jeffery
scheme or table, p. 2846 - 2848 (2010/07/06)
This Letter describes the synthetic challenges in synthesising key 1,4-cis-substituted cyclohexylamide intermediate 1 for our research programme. Five different routes address the major issues of selectivity to afford the cis product in isomerically pure
