1228291-64-2Relevant academic research and scientific papers
Structures of two novel trimeric stilbenes obtained by horseradish peroxidase catalyzed biotransformation of trans -resveratrol and (-)-ε-viniferin
Wilkens, Andrea,Paulsen, Jana,Wray, Victor,Winterhalter, Peter
experimental part, p. 6754 - 6761 (2011/08/06)
Two stilbenes, trans-resveratrol and (-)-ε-viniferin, as well as a mixture of both, were biotransformed using horseradish peroxidase and hydrogen peroxide. Under the applied conditions trans-resveratrol afforded one major product, which was identified as trans-δ-viniferin, a resveratrol-trans- dehydrodimer. Large-scale biotransformation of a mixture of trans-resveratrol and (-)-ε-viniferin yielded two novel resveratrol trimers, resviniferin A and resviniferin B, which were obtained in a pure form after fractionation by high-speed countercurrent chromatography and final purification by preparative HPLC. Their structures were established by means of mass spectrometry and 2D NMR spectroscopic analyses, including HSQC, HMBC, COSY, and ROESY.
