122835-69-2

Upstream product

• 122835-65-8 3-(α-formyl-α-cyanomethyl)-1-phenyl-4-(p-chlorobenzylidene)-5-pyrazolone 
• 100-63-0 phenylhydrazine 
• 122835-59-0 3-(4-isoxazolyl)-1-phenyl-4-(p-chlorobenzylidene)-5-pyrazolone 
• 122835-55-6 3-(α-dimethylaminomethylene-α-formylmethyl)-1-phenyl-4-(p-chlorobenzylidene)-5-pyrazolone 
• 71289-10-6 4-(4-chlorobenzylidene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one 

Relevant academic research and scientific papers

STUDIES IN VILSMEIER-HAACK REACTION: REACTION OF 3-METHYL-1-PHENYL-4-ARYLIDENE-5-PYRAZOLONE

The 3-methyl group in Ia, b has been found to undergo diformylation by Vilsmeier reagent to give the aminoacrolein derivatives (IIa, b).Treatment of IIa, b with different reagents affords the related 1-phenyl-4-arylidene-5-pyrazolone derivatives with different heterocyclic systems in the 3-position.The Vilsmeier reaction on pyrazolopyrazole (XIII) have been utilized to prove chemically that new heterocyclic system are formed only at the 3-position and no addition on the carbon-carbon double bond in the conjugated system O=C-C=C-(B) takes place.