1228358-90-4Relevant academic research and scientific papers
Ambient-temperature cobalt-catalyzed cycloaddition strategies to aromatic boronic esters
Auvinet, Anne-Laure,Harrity, Joseph P. A.,Hilt, Gerhard
supporting information; experimental part, p. 3893 - 3896 (2010/08/06)
Figure presented The room-temperature cobalt-catalyzed [4 + 2] cycloaddition of alkynylboronates and 1,3-dienes provides a convenient and general method for the synthesis of benzene-based aromatic boronic esters. Two complementary aromatization strategies involving in situ elimination and DDQ oxidation were explored, with the latter finding more generality. Finally, the potential of this technique to generate highly functionalized biaryls has been demonstrated via the synthesis of chiral (racemic) DMAP catalysts.
