1228439-45-9Relevant academic research and scientific papers
Microwave Assisted Synthesis and Antimicrobial Activity of Novel Pyrrolidine Derivatives
Jha, Anjali,Sreekanth, K.
, (2020)
Microwave assisted synthesis of 1-acetyl-2-benzylpyrrolidine-2-carboxylic acid and its derivatives has been developed with highly encouraging yields. 2-Benzyl-tert-butylpyrrolidine-1,2-dicarboxylate is used as an initial compound in the four steps synthes
Benzyl prolinate derivatives as novel selective KCC2 blockers
Pégurier, Cécile,Bosman, Nathalie,Collart, Philippe,Delporte, Marie-Laure,Leclercq, Karine,Lengelé, Sébastien,Kanduluru, Ananda Kumar,Meunier, Stéphane,Pacico, Nathalie,Vadali, Lakshmana Rao,Wagner, Alain,Wolff, Christian,Provins, Laurent
scheme or table, p. 2542 - 2545 (2010/07/04)
The discovery and optimization of a novel class of selective submicromolar KCC2 blockers is described. Details of synthesis and SAR are given together with ADME properties of selected compounds. A methylsulfone residue on the R1 phenyl group im
