1228468-93-6Relevant articles and documents
Direct, one-pot sequential reductive alkylation of lactams/amides with grignard and Organolithium reagents through lactam/amide activation
Xiao, Kai-Jiong,Luo, Jie-Min,Ye, Ke-Yin,Wang, Yu,Huang, Pei-Qiang
supporting information; experimental part, p. 3037 - 3040 (2010/07/05)
(Figure Presented) Be dazzled by the sequence: The first efficient and general one-pot method for the reductive bisalkylation of lactams/ amides with Grignard and organolithium reagents has been developed (see scheme; DTBMP = 2,6-di-tert-butyl-4methylpyridine, Tf=trifluoromethanesulfonyl).