122858-15-5Relevant articles and documents
Quinolone antibacterials: Synthesis and biological activity of carbon isosteres of the 1-piperazinyl and 3-amino-1-pyrrolidinyl side chains
Laborde,Kiely,Culbertson,Lesheski
, p. 1964 - 1970 (2007/10/02)
A series of 6-fluoro-1,4-dihydro-4-oxo-3-quinoline- and 1,8- naphthyridinecarboxylic acids, substituted at the 7-position with carbon- linked side chains, was synthesized and evaluated for antibacterial activity and DNA-gyrase inhibition. Structural modif
Antibacterial agents
-
, (2008/06/13)
The novel series of quinoline-, naphthyridine- and benzoxazine-carboxylic acids useful as antibacterial agents is described. Novel methods for preparing the compounds as well as novel intermediates are also described as are methods for their formulation a