327-51-5

Basic information

• Product Name: 1,4-Dibromo-2,5-difluorobenzene
• Synonyms: Benzene, 1,4-dibromo-2,5-difluoro-;2,5-Difluoro-1,4-Dibromrobenzene;1,4-Dibromo-2,5-difluorobenzene 98%;1,4-Dibromo-2,5-difluorobenzene98%;1,4-Difluoro-2,5-dibromobenzene;2,5-Difluoro-1,4-phenylene dibromide;2,5-Difluoro-1,4-ph;1,4-Dibromo-2,5-difl
• CAS NO: 327-51-5
• Molecular Formula: C₆H₂Br₂F₂
• Molecular Weight: 271.88
• EINECS: 206-317-2
• Product Categories: Bromine Compounds;Fluorine Compounds;Aryl;C6;Halogenated Hydrocarbons
• Mol File: 327-51-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 60-62 °C(lit.)
• Boiling Point: 96 °C20 mm Hg(lit.)
• Flash Point: 96°C/20mm
• Appearance: white adhering crystals
• Density: 2.1030 (rough estimate)
• Vapor Pressure: 0.297mmHg at 25°C
• Refractive Index: 1.5151 (estimate)
• Storage Temp.: Room temperature.
• Solubility: almost transparency in Methanol
• Water Solubility: insoluble
• BRN: 2250095
• CAS DataBase Reference: 1,4-Dibromo-2,5-difluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dibromo-2,5-difluorobenzene(327-51-5)
• EPA Substance Registry System: 1,4-Dibromo-2,5-difluorobenzene(327-51-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 327-51-5(Hazardous Substances Data)

Usage

Chemical Properties

white adhering crystals

Uses

Different sources of media describe the Uses of 327-51-5 differently. You can refer to the following data:
1. 1,4-Dibromo-2,5-difluorobenzene has been used in the preparation of 1,2,4,5-tetrakis(phosphino)-3,6-difluorobenzenes and poly(2,5-difluoro-2?,5?-didodecyl-4,4?-biphenylylene.
2. 1,4-Dibromo-2,5-difluorobenzene has been used in the preparation of:1,2,4,5-tetrakis(phosphino)-3,6-difluorobenzenespoly(2,5-difluoro-2′,5′-didodecyl-4,4′-biphenylylene

InChI:InChI=1/C6H2Br2F2/c7-3-1-5(9)4(8)2-6(3)10/h1-2H

Upstream product

• 540-36-3 para-difluorobenzene 
• 124-38-9 carbon dioxide 

Downstream Products

• 303006-90-8 1,4-difluoro-2,5-di(4',4',5',5'-tetramethyl[1',3',2']dioxaborolan-2'-yl)benzene 
• 357405-75-5 4-bromo-2,5-difluorobenzaldehyde 
• 862098-75-7 (4-bromo-2,5-difluorophenyl)(6-chloro-3-pyridinyl)methanone 
• 862098-67-7 1-(4-bromo-2,5-difluorophenyl)-1-(4-pyridinyl)methanimine 
• 862098-77-9 (4-bromo-2,5-difluorophenyl)[6-(methyloxy)-3-pyridinyl]methanone 
• 862098-73-5 (2,5-dibromo-3,6-difluorophenyl)[6-(methyloxy)-3-pyridinyl]methanone 
• 1323950-16-8 1,4-dibromo-2,5-bis-dichloromethyl-3,6-difluoro-benzene 
• 1323950-17-9 2,5-dibromo-3,6-difluoro-benzene-1,4-dicarbaldehyde 
• 1426175-96-3 1,4-difluoro-2,5-ditritiobenzene 
• 1135467-32-1 (1,4-bis(2-n-hexyl-5-thienyl)-2,5-bis(methylsulfinyl)benzene) 
• 1417332-30-9 (4-bromo-2,5-difluorophenyl)trimethylsilane 
• 1193162-21-8 4-bromo-2,5-difluoro-benzoic acid methyl ester 
• 1084953-18-3 methyl 4-bromo-5-fluoro-2-methoxybenzoate 
• 1084953-16-1 methyl 5-fluoro-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 

Relevant articles and documents

Bromination of aromatic compounds using an Fe2O 3/zeolite catalyst

The catalytic bromination of non-activated aromatic compounds has been achieved using an Fe2O3/zeolite catalyst system. FeBr 3 was identified as the catalytic species, formed in situ from HBr and Fe2O3. The catalyst was easy-to-handle and cost effective and could also be recycled. The reaction system was also amenable to the one-pot sequential bromination/C-C bond formation of benzene.

PHOTOCHEMICAL BROMINATION OF ARENES. 2. FLUOROBENZENE DERIVATIVES (1)

Photochemically induced reaction of fluorobenzene and a range of polyfluorobenzenes, both in an excess of the arene and with fluorotrichloromethane as solvent, gave isolable adducts only with fluorobenzene, the isomeric difluorobenzenes, and in very small yield with 1,3,5-trifluorobenzene.These adducts were identified by combustion analysis, mass spectrometry, and n.m.r. techniques (1H, 13C, 19F).In every case, the expected substitution products accompanied these adducts, and in the more fully fluorinated benzene derivatives substitution was the only process observed.Fluorotrichloromethane encouraged the formation of adducts, but the concurrent formation of substantial amounts of substitution products suggested that adducts are not the necessary precursors of the substitution products, in contrast with other systems.