1228593-74-5Relevant academic research and scientific papers
Noncatalytic electrophilic oxyalkylation of some five-membered heterocycles with 2-(trifluoroacetyl)-1,3-azoles
Khodakovskiy, Pavel V.,Mykhailiuk, Pavel K.,Volochnyuk, Dmitriy M.,Tolmachev, Andrey A.
experimental part, p. 979 - 984 (2010/05/18)
A set of electrophilic 2-(trifluoroacetyl)-1,3-azoles demonstrated- excellent activity in the C-oxyalkylation of pyrrole, furan, thiophene, 1,3-thiazole, and 1,2-oxazole derivatives. The reaction conditions and the yields of the corresponding trifluoromethyl-substituted alcohols depend strongly on both the electronic and steric nature of the 1,3-azole unit. Georg Thieme Verlag Stuttgart ? New York.
