122891-92-3 Usage
Uses
Used in Pharmaceutical Synthesis:
1-Benzenesulfonyl-piperidine-4-carboxylic acid is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity enable the creation of a wide range of bioactive compounds with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Benzenesulfonyl-piperidine-4-carboxylic acid serves as a valuable building block for the design and synthesis of new drugs. Its ability to engage in diverse chemical reactions facilitates the development of innovative molecules with improved pharmacological properties.
Used in Drug Discovery and Development:
1-Benzenesulfonyl-piperidine-4-carboxylic acid plays a significant role in drug discovery and development processes. Its potential applications in creating novel bioactive compounds contribute to the advancement of therapeutic options for various diseases and conditions.
Used in Organic Compound Synthesis:
Beyond its pharmaceutical applications, 1-Benzenesulfonyl-piperidine-4-carboxylic acid is also employed in the synthesis of various organic compounds. Its versatility in chemical reactions makes it a useful component in the development of new organic materials and chemicals for different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 122891-92-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,8,9 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 122891-92:
(8*1)+(7*2)+(6*2)+(5*8)+(4*9)+(3*1)+(2*9)+(1*2)=133
133 % 10 = 3
So 122891-92-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO4S/c14-12(15)10-6-8-13(9-7-10)18(16,17)11-4-2-1-3-5-11/h1-5,10H,6-9H2,(H,14,15)/p-1
122891-92-3Relevant articles and documents
CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF
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Paragraph 0554; 0556, (2019/04/05)
Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the use of the compound in treating caspase-related diseases.
Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors
Rossi, Cristina,Porcelloni, Marina,D'Andrea, Piero,Fincham, Christopher I.,Ettorre, Alessandro,Mauro, Sandro,Squarcia, Antonella,Bigioni, Mario,Parlani, Massimo,Nardelli, Federica,Binaschi, Monica,Maggi, Carlo A.,Fattori, Daniela
supporting information; experimental part, p. 2305 - 2308 (2011/05/15)
We report here the strategy used in our research group to find a new class of histone deacetylase (HDAC) inhibitors. A series of N-substituted 4-alkylpiperazine and 4-alkylpiperidine hydroxamic acids, corresponding to the basic structure of HDAC inhibitors (zinc binding moiety-linker-capping group) has been designed, prepared, and tested for HDAC inhibition. Linker length and aromatic capping group connection were systematically varied to find the optimal geometric parameters. A new series of submicromolar inhibitors was thus identified, which showed antiproliferative activity on HCT-116 colon carcinoma cells.
