122899-26-7Relevant academic research and scientific papers
Copper(I)-Catalyzed Tandem One-Pot Synthesis of 2-Arylthiobenzothiazoles and 2-Arylthiobenzoxazoles in Water
Liu, Xing,Zhang, Shi-Bo,Zhu, Hui,Dong, Zhi-Bing
, p. 11703 - 11711 (2018/10/02)
An efficient tandem process for the preparation of 2-arylthiobenzothiazoles has been developed. By condensation of 2-aminobenzenethiol with tetramethylthiuram disulfide (TMTD), 2-mercaptobenzothiazoles was in situ generated, which susequently underwent coupling with iodobenzenes to give the desired 2-arylthiobenzothiazoles fluently in a one-pot manner. This method can also be used for the synthesis of 2-arylthiobenzoxazoles. Inexpensive metal catalyst and ligand, mild reaction temperature, and water as solvent make this protocol practically valuable and useful in organic synthesis.
Copper-catalyzed direct thiolation of benzoxazole with diaryl disulfides and aryl thiols
Fukuzawa, Shin-ichi,Shimizu, Eiji,Atsuumi, Yuka,Haga, Masatake,Ogata, Kenichi
scheme or table, p. 2374 - 2376 (2009/07/19)
The cross-coupling reaction of benzoxazole with aryl thiols using the CuI/2,2′-bipyridine complex as a catalyst in DMF at 80 °C under oxygen produced the corresponding aryl thioethers in moderate to good yields. The coupling reaction with diaryl disulfide
