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1229020-03-4

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1229020-03-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1229020-03-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,9,0,2 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1229020-03:
(9*1)+(8*2)+(7*2)+(6*9)+(5*0)+(4*2)+(3*0)+(2*0)+(1*3)=104
104 % 10 = 4
So 1229020-03-4 is a valid CAS Registry Number.

1229020-03-4Upstream product

1229020-03-4Relevant articles and documents

Utilization of halogen bond in lead optimization: A case study of rational design of potent phosphodiesterase type 5 (PDE5) inhibitors

Xu, Zhijian,Liu, Zheng,Chen, Tong,Chen, Tiantian,Wang, Zhen,Tian, Guanghui,Shi, Jing,Wang, Xuelan,Lu, Yunxiang,Yan, Xiuhua,Wang, Guan,Jiang, Hualiang,Chen, Kaixian,Wang, Shudong,Xu, Yechun,Shen, Jingshan,Zhu, Weiliang

, p. 5607 - 5611 (2011)

For proof-of-concept of halogen bonding in drug design, a series of halogenated compounds were designed based on a lead structure as new inhibitors of phosphodiesterase type 5. Bioassay results revealed a good correlation between the measured bioactivity and the calculated halogen bond energy. Our X-ray crystal structures verified the existence of the predicted halogen bonds, demonstrating that the halogen bond is an applicable tool in drug design and should be routinely considered in lead optimization.

PHENYL PYRIMIDONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, PREPARATION METHODS AND USES THEREOF

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Page/Page column 19-20, (2011/11/12)

The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following f

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