1229020-08-9

Upstream product

• 7152-15-0 ethyl 4-methyl-3-oxo-pentanoate 
• 63874-26-0 2-n-propoxybenzamidine 
• 1229019-44-6 5-bromo-6-isopropyl-2-(2-propoxyphenyl)pyrimidin-4(3H)-one 
• 1229019-43-5 2-(2-n-propoxyphenyl)-6-isopropylpyrimid-4(3H)-one 

Downstream Products

• 1229017-07-5 5-bromo-6-isopropyl-2-[2-n-propoxyl-5-(4-methyl-1-piperazinylsulfonyl)phenyl]pyrimid-4(3 H)-one 
• 1229017-23-5 3-(5-bromo-4-isopropyl-6-oxo-1,6-dihydropyrimidin-2-yl)-N-(2-morpholinoethyl)-4-propoxybenzenesulfonamide 
• 1229017-25-7 3-(5-bromo-4-isopropyl-6-oxo-1,6-dihydropyrimidin-2-yl)-N-(2-(diethylamino)ethyl)-4-propoxybenzenesulfonamide 

Relevant academic research and scientific papers

Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5

The substituents both at the 6-position of the 5-bromopyrimidinone ring and at the 5′-position of the phenyl ring of 5-bromopyrimidin-4(3H)-ones were explored. 5-Bromo-6-isopropyl-2-(2-propoxy-phenyl)pyrimidin-4(3H)-one was identified as a new scaffold fo

PHENYL PYRIMIDONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, PREPARATION METHODS AND USES THEREOF

The present invention relates to a class of phenylpyrimidone compounds, the pharmaceutical composition, the preparation method and the use thereof. More specifically, the present invention relates to a type of phenylpyrimidone compounds of the following f