122908-65-0Relevant academic research and scientific papers
ELECTROPHILIC AMINATION: ENANTIOSELECTIVE SYNTHESES OF D-ALLOTHREONINE AND L-THREONINE
Genet, J. P.,Juge, S.,Mallart, S.
, p. 6765 - 6768 (1988)
Starting from inexpensive polyhydroxybutanoate (PHB), D-allothreonine 1 and L-threonine 2 were synthetized by a sequence involving a diastereoselective electrophilic amination.When (R) 3-hydroxybutanoic acid was protected as dioxanone 9 very good yield (>95percent) and high diastereomeric excess (>99percent) were obtained in the amination step.
