1229357-78-1Relevant academic research and scientific papers
Seebach's conjunctive reagent enables double cyclizations
Chandler, Brent D.,Roland, Jason T.,Li, Yukai,Sorensen, Erik J.
, p. 2746 - 2749 (2010)
(Figure presented) When ketones flanked on both sides by nucleophilic atoms react with Seebach's nitropropenyl pivaloate reagent, direct couplings take place to give two new ring systems and three bonds. Cis-ring fusions are observed in unions leading to 5,5-, 5,6-, and 6,6-bicycles. Densely functionalized and rigid frameworks may be rapidly formed by the chemistry described herein.
