122942-92-1

Basic information

• Product Name: 4-(3-dimethylaminopropoxy)dibenzothiepin-11(6H)-one
• CAS NO: 122942-92-1
• Molecular Weight: 327.447
• Mol File: 122942-92-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-dimethylaminopropoxy)dibenzothiepin-11(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-dimethylaminopropoxy)dibenzothiepin-11(6H)-one(122942-92-1)
• EPA Substance Registry System: 4-(3-dimethylaminopropoxy)dibenzothiepin-11(6H)-one(122942-92-1)

Safety Data

• Hazardous Substances Data: 122942-92-1(Hazardous Substances Data)

Upstream product

• 82387-29-9 4-Methoxydibenzothiepin-11(6H)-one 
• 5407-04-5 3-(dimethylamino)propyl chloride hydrochloride 
• 122942-94-3 4-hydroxydibenzothiepin-11(6H)-one 

Relevant articles and documents

POTENTIAL ANTIDEPRESSANTS: SYNTHESIS OF TWO 4-(AMINOALKOXY)DIBENZOTHIEPIN-11(6H)-ONES

Heating of 4-methoxydibenzothiepin-11(6H)-one with pyridine hydrochloride to 225 to 235 deg C effected demethylation and gave IV.Its sodium salt reacted with 3-dimethylaminopropyl chloride in ethanol and afforded the 4-(3-dimethylaminopropoxy) compound II.The isomeric ether III was prepared via the 4-(4-bromobutoxy) compound V.Hydrochloride of II (VUFB-17033) inhibitied mildly the binding of 3H>desipramine in rat hypothalamus, had antireserpine activity in rats, mild anticonvulsant effect, and antihypoxic effect in the test of nitrogen anoxia in mice.