1229681-49-5

Basic information

• Product Name: (E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2H-chromen-3-yl)prop-2-en-1-one
• CAS NO: 1229681-49-5
• Molecular Weight: 361.224
• Mol File: 1229681-49-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2H-chromen-3-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2H-chromen-3-yl)prop-2-en-1-one(1229681-49-5)
• EPA Substance Registry System: (E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2H-chromen-3-yl)prop-2-en-1-one(1229681-49-5)

Safety Data

• Hazardous Substances Data: 1229681-49-5(Hazardous Substances Data)

Upstream product

• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 57543-40-5 6-methoxy-2H-chromene-3-carbaldehyde 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Chromene-based synthetic chalcones as potent antileishmanial agents: Synthesis and biological activity

Two types of regioisomeric chromene-based chalcones namely, 1-(6-methoxy-2H-chromen-3-yl)-3-phenylpropen-1-ones and 3-(6-methoxy-2H-chromen- 3-yl)-1-phenylpropen-1-ones were prepared and investigated for their antileishmanial activity against promastigotes form of Leishmania major. The obtained results from in vitro biological assays indicated that chloro-substituted 1-(6-methoxy-2H-chromen-3-yl)-3-phenylpropen-1-ones exhibited excellent activity against Leishmania major at non-cytotoxic concentrations.