122993-59-3

Usage

Uses

Used in Organic Synthesis:
2-METHYLISOINDOLIN-4-AMINE is utilized as a building block in organic synthesis, contributing to the creation of various complex organic compounds. Its presence in these syntheses is crucial for the development of new chemical entities.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-METHYLISOINDOLIN-4-AMINE serves as a key component in the design and synthesis of new drug molecules. Its unique structure allows it to be a promising candidate for the development of innovative therapeutic agents.
Used in Dyes and Pigments Production:
2-METHYLISOINDOLIN-4-AMINE is also employed in the production of dyes and pigments, where its chemical properties contribute to the color and stability of these products.
Used in Material Science:
2-METHYLISOINDOLIN-4-AMINE's potential application extends to the development of new materials, where its unique structure and properties can be harnessed to create novel substances with specific characteristics for various industries.

Upstream product

• 2593-81-9 N-methyl-3-nitrophthalimide 
• 2257-85-4 4-amino-2-methyl-1H-isoindole-1,3(2H)-dione 

Relevant academic research and scientific papers

NOVEL QUINOXALINEDIONE DERIVATIVES, THEIR PREPARATION AND USE

A compound having the formula or a pharmaceutically acceptable salt thereof wherein R is hydrogen or hydroxy; R1 is hydrogen, alkyl, arylalkyl, (CH2)nOH, or (CH2) NR7R8; R5 and R6 are each independently hydrogen, halogen, NO2, CN, CF3, SO2NR7R8, PO3R9R10, alkyl, alkenyl, alkynyl, (CH2)nCONR7R8, (CH2)nCO2R10, NHCOR11, wherein R7 and R8 are each independently hydrogen or alkyl or together R7 and R8 form a ring of from three to seven atoms, R9 is hydrogen or alkyl, R10 is hydrogen or alkyl, R11 is hydrogen or alkyl, and n is an integer of from zero to four; A is a ring of five to seven atoms fused with the benzo ring at the positions marked a and b, and formed by the following bivalent radicals: a-NR12—CHR13—CHR14-b, a-CHR13—CHR14—NR12-b, a-CHR13—NR12—CHR14-b, a-CHR14—CH2—NR12—CHR13-b, a-CHR13—NR12—CH2—CHR14-b, a-CH2—CH2—CHR13—NR12-b, a-NR12—CHR12—CHR13—CH2—CH2-b, a-CH2—CH2—NR12—CH2—CH2-b, a-CH2—CH2—CH2NR12—CH2-b, a-CH2—NR12—CH2—CH2-b a-CH2—CH2—CH2—CH2—NR12-b, a-NR12—CH2—CH2—CH2—CH2-b, wherein R12 is hydrogen, CH2CH2OH, or alkyl, and R13 and R14 are each independently hydrogen, CN, CONH2, CH2NH2, CH2OH, alkyl, arylalkyl, alkenyl, or CO2R15, wherein R15 is hydrogen or alkyl. The compounds are useful in the treatment of disorders of mammals, responsive to the blockade of glutamic and aspartic acid receptors. Processes for preparing the compounds and novel intermediate useful in the processes are also included.

Synthesis and Mass Spectrometric Fragmentation of Dihydroisoindole Derivatives

C-8-substituted N-methyl-1,2,3,4-tetrahydroisoquinoline radical cations lose the complete substituent in a one step reaction giving rise to an unexpected ion at m/z 146, which is probably identical with the dihydroisoindolylmethyl-cation A.The dihydroisoindoles 1, 10, and 16 were prepared as potentially alternative precursors of ion A.Hovever, the ion at m/z 146 in their EI mass spectra is of very low intensity, so CID-experiments for structural comparison could not be performed.The electron impact induced fragmentations of 1, 10, and 16 are discussed.