123016-51-3

Usage

Uses

Used in Pharmaceutical Industry:
2,3,4,6-Tetrafluorobenzoyl chloride is used as a key intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs with improved properties and therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3,4,6-tetrafluorobenzoyl chloride is utilized as a building block in the creation of insecticides and herbicides, enhancing the effectiveness of these products in controlling pests and weeds.
Used in Organic Synthesis:
2,3,4,6-Tetrafluorobenzoyl chloride is employed as a reagent in organic synthesis, facilitating the formation of complex organic molecules for various applications, including the development of new materials and compounds.
Used in Dyes and Pigments Production:
As a precursor in the production of dyes and pigments, 2,3,4,6-tetrafluorobenzoyl chloride plays a crucial role in the creation of colorants for various industries, such as textiles, plastics, and printing inks.

InChI:InChI=1/C7HClF4O/c8-7(13)4-2(9)1-3(10)5(11)6(4)12/h1H

Upstream product

• 32890-92-9 2,3,4,6-tetrafluorobenzoic acid 
• 1551-39-9 2,4,5,6-tetrafluoroisophthalic acid 

Downstream Products

• 133434-01-2 diethyl 2,3,4,6-tetrafluorobenzoylmalonate 
• 123016-52-4 ethyl 2,3,4,6-tetrafluorobenzoylacetate 
• 53001-70-0 2,4,5,6-tetrafluorobenzyl alcohol 
• 1109138-77-3 N-(2-chloroethyl)-2-(2,3,4,6-tetrafluorophenyl)acid amide 
• 174312-99-3 5-Benzylamino-8-chloro-1-cyclopropyl-7-fluoro-6-nitro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 127625-07-4 5-Benzylamino-8-chloro-1-cyclopropyl-7-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 123016-54-6 ethyl 2-(2,3,4,6-tetrafluorobenzoyl)-3-cyclopropylacrylate 

Relevant academic research and scientific papers

QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME

The present disclosure relates to quinolin-4-one and 4(1H)-cinnolinone compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.

Preparation method of tetrafluorobenzene methanol

Belonging to the technical field of organic synthesis, the invention discloses a preparation method of tetrafluorobenzene methanol. The method includes: reacting tetrafluorobenzoic acid with thionyl chloride to produce tetrafluorobenzoyl chloride, then taking tetrafluorobenzoyl chloride as the raw material, and conducting reduction in water with sodium borohydride activated by an ether solvent toobtain tetrafluorobenzene methanol. According to the invention, the ether solvent and sodium borohydride are subjected to complexing to activate sodium borohydride, water is adopted as the solvent forreduction, the reaction yield is high, the reductant sodium borohydride can complete the reaction at a catalytic amount, and the reaction process is greener and more environmentally friendly.

Imidazo- and triazoloquinolones as antibacterial agents. Synthesis and structure-activity relationships

4,5-Disubstituted 6-cyclopropyl-6,9-dihydro-9-oxo-1H-imidazo- (30-32) and triazolo[4,5-f]quinoline-8-carboxylic acids (33-35) were synthesized starting from 5,6-diaminoquinolones 25. The imidazoquinolones 30-32 were equal or superior to the corresponding triazoloquinolone analogues 33-35 in in vitro antibacterial activity. As for the C-5 substituents, a fluorine atom was the most favorable of the three groups, H, F, and Cl. Among the compounds prepared, 4-(cyclic amino)-5-fluoro-imidazoquinolones 31a-d showed potent and well-balanced antibacterial activity against both gram-positive and gram- negative bacteria. Structure-activity relationships for the C-4 substituents (cyclic amino groups) were also examined in detail.

Oxo quinoline derivatives

A quinoline derivative of the formula STR1 wherein Z is an amino group or a halogen atom, and R1, R2 and R3 are the same or different and each represents a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, and an ester thereof and a salt of the derivative or the ester and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful as antibacterial agents.