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Pneumocandin B0, 1-[(4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-5-[(4-methylphenyl)thio]-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]is a complex lipopeptide antifungal agent belonging to the echinocandin class. It is derived from the fungus Zalerion arboricola and exhibits potent inhibitory activity against the synthesis of β-(1,3)-D-glucan, a crucial component of the fungal cell wall. Pneumocandin B0, 1-[(4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-5-[(4-methylphenyl)thio]-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]is primarily utilized as a reference standard in research and pharmaceutical development for studying antifungal agents and their mechanisms of action. Pneumocandin B0 has demonstrated potential as a treatment for fungal infections, especially those caused by resistant strains.

1230487-11-2

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1230487-11-2 Usage

Uses

Used in Pharmaceutical Research and Development:
Pneumocandin B0, 1-[(4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-5-[(4-methylphenyl)thio]-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]is used as a reference standard for the study of antifungal agents and their mechanisms of action. It aids in understanding the effectiveness of echinocandins against fungal infections and contributes to the development of new antifungal drugs.
Used in Antifungal Treatments:
In the medical industry, Pneumocandin B0, 1-[(4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-5-[(4-methylphenyl)thio]-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]is used as a potential treatment for fungal infections. It is particularly valuable for addressing infections caused by resistant strains due to its potent inhibitory activity against β-(1,3)-D-glucan synthesis, which is essential for the integrity of the fungal cell wall.
Used in Drug Resistance Studies:
Pneumocandin B0, 1-[(4R,5R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-5-[(4-methylphenyl)thio]-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]is utilized in research to investigate drug resistance in fungi. Understanding the mechanisms by which fungi develop resistance to antifungal agents like Pneumocandin B0 can inform the development of more effective treatments and strategies to combat resistant strains.

Check Digit Verification of cas no

The CAS Registry Mumber 1230487-11-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,0,4,8 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1230487-11:
(9*1)+(8*2)+(7*3)+(6*0)+(5*4)+(4*8)+(3*7)+(2*1)+(1*1)=122
122 % 10 = 2
So 1230487-11-2 is a valid CAS Registry Number.

1230487-11-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name CFC

1.2 Other means of identification

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Other names CFC

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

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More Details:1230487-11-2 SDS

1230487-11-2Relevant academic research and scientific papers

Process for preparation of Caspofungin acetate

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Page/Page column 5, (2010/07/08)

A process for making caspofungin acetate comprising the steps of: A. selectively dehydrating pneumocandin Bo to obtain a nitrile;B. reducing the nitrile to primary amine;C. reacting the primary amine with an arylthiol in a suitable solvent to obtain a thi

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