123065-61-2Relevant academic research and scientific papers
WDR5 INHIBITORS AND MODULATORS
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Paragraph 0504; 0713, (2020/04/24)
Described are imino-azacycle-benzamide compounds compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and c
Broad substrate specificity of the amide synthase in S. hygroscopicus -new 20-membered macrolactones derived from geldanamycin
Eichner, Simone,Eichner, Timo,Floss, Heinz G.,Fohrer, Joerg,Hofer, Edgar,Sasse, Florenz,Zeilinger, Carsten,Kirschning, Andreas
supporting information; experimental part, p. 1673 - 1679 (2012/03/12)
The amide synthase of the geldanamycin producer, Streptomyces hygroscopicus, shows a broader chemoselectivity than the corresponding amide synthase present in Actinosynnema pretiosum, the producer of the highly cytotoxic ansamycin antibiotics, the ansamit
