123124-75-4

Upstream product

• 106-39-8 bromochlorobenzene 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 102994-16-1 1-[(4-Chloro-phenyl)-(4-trifluoromethyl-phenyl)-methyl]-1H-imidazole 
• 508211-48-1 methyl 2-{(4-chlorophenyl)[4-(trifluoromethyl)phenyl]methoxy}-5-nitrobenzoate 

Relevant academic research and scientific papers

BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF

Novel benzene derivatives represented by the formula (I) : wherein R1, R4 and R6 each independently represents a hydrogen atom, a halogen atom or a hydrocarbon group, R2 represents a hydrocarbon group or a heterocyclic group, R3 represents a hydrocarbon group, NR7'R7 or OR8 (wherein R7' represents a hydrogen atom or a hydrocarbon group, R7 represents a non-aromatic group, or R7' and R7 may form a ring with the adjacent nitrogen atom, and R8 represents a hydrocarbon group or a heterocyclic group), R5 represents a hydrocarbon group or a heterocyclic group (except for a quinolyl group), R5' represents a hydrogen atom, or a hydrocarbon group, or R5 and R5' may form a ring with the adjacent nitrogen atom, and R5" represents a hydrogen atom or a hydrocarbon group, which have vanilloid receptor agonist activity and are useful as a drug such as an analgesic and an agent for preventing and/or treating urinary frequency and/or urinary incontinence.

Synthesis, Absolute Configuration and Circular Dichroism of Some Diarylmethane Derivatives

Synthesis and assignment of the absolute configuration of different types of compounds bearing the diarylmethane moiety is presented.The absolute configuration was determined using chemical correlation and CD approaches based on the sign of the O-O vibronic transition within the α-aromatic (1Lb) band of the substituted phenyl chromophore.