123155-06-6Relevant articles and documents
Per(3-deoxy)-γ-cyclomannin: A non-glucose cyclooligosaccharide featuring inclusion properties
Yang, Cheng,Yuan, De-Qi,Nogami, Yasuyoshi,Fujita, Kahee
, p. 4641 - 4644 (2003)
Per(3-deoxy)-γ-cyclomannin has been efficiently synthesized by a three-step procedure starting from natural γ-cyclodextrin, and proved to be capable of binding naphthalenesulfonate in aqueous solution and solubilizing C60 in water. For the first time it was spectrally evidenced that a non-glucose cyclooligosaccharide did form inclusion complexes with conventional organic guest molecules.
New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands
Aime, Silvio,Gianolio, Eliana,Arena, Francesca,Barge, Alessandro,Martina, Katia,Heropoulos, George,Cravotto, Giancarlo
scheme or table, p. 370 - 379 (2009/03/11)
Bridged cyclodextrin dimers and trimers, in which respectively two and three hydrophobic cavities lie in close proximity, display much higher binding affinities and molecular selectivities than do parent cyclodextrins (CDs). By joining βCD units with links inserted at different positions (2-2′, 3-2′, 6-2′ or 6-2′-6″) and interposing spacers of different lengths and shapes, multicavity structures can be synthesized that are precisely tailored to fit specific guest molecules. This enzyme-mimicking strategy can also be used to generate stable supramolecular adducts. A series of CD dimers and trimers was prepared in good yields by carrying out the critical synthetic steps under power ultrasound (US) or microwave (MW) irradiation. Starting from azide and acetylenic CD derivatives, we exploited an efficient MW-promoted Huisgen 1,3-dipolar cycloaddition in the presence of Cu(I) salts. The resulting bridged CD derivatives gave stable adducts with magnetic-resonance-imaging contrast agents (MRI CAs) containing gadolinium(III) chelates. These inclusion complexes were found to be 2 to 3 orders of magnitude more stable than those formed by βCD and to be endowed with high relaxivity values.
Synthetic 6-O-methylglucose-containing polysaccharides (sMGPs): Design and synthesis
Meppen, Malte,Wang, Yonghui,Cheon, Hwan-Sung,Kishi, Yoshito
, p. 1941 - 1950 (2007/10/03)
With the hope of mimicking the chemical and biological properties of natural 6-O-methyl-D-glucose-containing polysaccharides (MGPs), synthetic 6-O-methyl-D-glucose-containing polysaccharides (sMGPs) were designed and synthesized from α-, β-, and y-cyclode
