1232-43-5

Upstream product

• 18210-86-1 6-allyl-7-hydroxy-5-methoxyflavone 
• 7446-08-4 selenium(IV) oxide 
• 54437-44-4 1-(6-hydroxy-4-methoxy-benzofuran-5-yl)-3t-phenyl-propenone 
• 71-36-3 butan-1-ol 
• 74047-33-9 4-allyloxy-2-hydroxy-3-iodo-6-methoxyacetophenone 
• 54437-44-4 1-(6-hydroxy-4-methoxybenzo[b]furan-5-yl)-3-phenylprop-2-en-1-one 
• 82-57-5 visnagin 
• 100-52-7 benzaldehyde 
• 484-27-5 5-acetyl-4-methoxybenzofuran-6-ol 
• 77693-06-2 4-allyloxy-2-benzoyloxy-3-iodo-6-methoxyacetophenone 
• 77693-07-3 4-allyloxy-2-hydroxy-3-iodo-6-methoxydibenzoylmethane 
• 77693-08-4 7-allyloxy-8-iodo-5-methoxyflavone 
• 104837-41-4 ω-Benzoatovisnaginone 

Downstream Products

• 412027-80-6 7-hydroxy-5-methoxy-4-oxo-2-phenyl-4H-chromene-6-carbaldehyde 
• 69367-25-5 5-hydroxyfurano(4'',5''-6,7)flavone 
• 104837-41-4 ω-Benzoatovisnaginone 
• 150036-33-2 6,7-dihydroxy-5-methoxyflavone 
• 1616883-49-8 C₂₀H₁₄O₄ 
• 1616883-51-2 C₂₀H₁₆O₅ 
• 1616883-50-1 9-allyl-4-hydroxy-7-phenyl-5H-furo[3,2-g]chromen-5-one 
• 1616883-52-3 8-allyl-7-hydroxy-5-methoxy-4-oxo-2-phenyl-4H-chromene-6-carbaldehyde 

Relevant academic research and scientific papers

Design, synthesis and structure-activity relationship of novel semi-synthetic flavonoids as antiproliferative agents

Various flavonoid scaffold based derivatives viz furochalcones (3a-e, 6a-d and 9a-d), furoflavones (10a-d, 11a-d, 12a-d, 18a&b), flavones (21a-d), furoaurones (13a,b, 14a-d and 15a-d) and 7-styrylfurochromones (22a-d and 25a-e) were designed and synthesiz

Synthesis and anticonvulsant activity of certain substituted furochromone, benzofuran and flavone derivatives

Synthesis of furochromone, 2-phenylchromone (flavone) and benzofuran derivatives substituted with thiosemicarbazide or thiazolidin-4-one moieties were accomplished. All the newly synthesized compounds were tested for their anticonvulsant activity in both subcutaneous pentylenetetrazole induced seizures (scPTZ) and maximal electric shock induced seizures (MES) tests using valproic acid and phenytoin respectively as reference standards. The most active compounds in scPTZ model were 1c, 2b, 5a and 7e showing 100% protection at 300 mg/kg upon intraperitoneal administration. Also, the effect of pre-treatment of three of the most active compounds (1c, 2b, 5a) on 4-amino pyridine-induced lethality in mice was investigated. Pre-treatment with these compounds significantly increased the latency for clonic and tonic seizures and prevented 4-amino pyridine induced death. Hence, this provides evidence for anticonvulsant activity of these compounds, and a neuroprotective activity for them. The structure - activity relationship was studied based on the obtained data.

Synthesis of 6- and 9-alkylaminomethyl furoflavones as gastroprotective agents

The synthesis of 9- and 6-alkylaminomethyl furoflavones 5a, b, 9a-c, 13a, b, 15a-g and 18 from the naturally occurring chromones visnagin and khellin. Gastroprotective potency of these compounds in the ethanol damage model was determined. The results indicate that, through appropriate substitution, furoflavones can be obtained that are gastroprotective.

Reaction and antimicrobial activity of 1-arylethylene benzofuranyl ketone derivatives

Interaction of benzalvisnaginone or khellinone derivatives with thiourea gives the tetrahydropyrimidin-2-thione derivatives which are condensed with chloroacetic acid in acetic anhydride to form thiazolo[3,2-a]pytimidin-3-one. Its behaviour towards benzal

A Convenient Synthesis of Pinnatin

The new synthesis of pinnatin (I) involves conversion of 4-allyloxy-2-hydroxy-3-iodo-6-methoxyacetophenone (V) into 7-allyloxy-8-iodo-5-methoxyflavone (III) by benzoylation, Baker-Venkataraman migration and cyclisation of the formed dibenzoylmethane (VII)