123225-98-9Relevant academic research and scientific papers
Therapeutic uses of tri-aryl acid derivatives
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Page/Page column 229, (2010/10/20)
The use of triaryl acid derivatives of formula (I) and their pharmaceutical compositions as PPAR ligand receptor binders. The PPAR ligand receptor binders of this invention are useful as agonists or antagonists of the PPAR receptor.
Therapeutic uses of quinoline derivatives
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, (2008/06/13)
A method for mediating the activity of PPAR-γ receptor comprising contacting said PPAR-γ receptor with a compound of formula I defined herein. Also disclosed is the treatment of a patient suffering from a physiological disorder capable of being modulated
Quinoline derivatives and their use as antagonists of leukotriene D4
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, (2008/06/13)
This invention relates to quinolinyl-diaryl compounds and their use as leukotriene D4 antagonists for the treatment of hypersensitive disorders.
Development of a Novel Series of (2-quinolinylmethoxy)phenyl-Containing Compounds as High-Affinity Leukotriene D4 Receptor Antagonists. 2. Effects of an Additional Phenyl Ring on Receptor Affinity
Huang, Fu-Chih,Galemmo, Robert A.,Johnson, William H.,Poli, Gregory B.,Morrissette, Matthew M.,et al.
, p. 1194 - 1200 (2007/10/02)
This series of reports describe the development of orally active, highly potent, specific antagonists of the peptidoleukotrienes containing a (2-quinolinylmethoxy)phenyl moiety.The compounds reported in this paper contain an additional phenyl ring, which
