123226-30-2Relevant academic research and scientific papers
Therapeutic uses of PPAR mediators
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, (2008/06/13)
Use of PPAR mediators, and their pharmaceutical compositions, as ATP binding cassette transporter 1 (ABC-1) expression modulators, wherein the PPAR ligand receptor agonists of this invention are useful as inducers of ABC-1 expression.
Therapeutic uses of di-aryl acid derivatives
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, (2008/06/13)
The use of diaryl acid derivatives of formula (I) or pharmaceutically acceptable salts, N-oxides, hydrates or solvates thereof, wherein the variables shown are defined in the disclosure, and their pharmaceutical compositions as PPAR ligand receptor binders. The PPAR ligand receptor binders of this invention are useful as agonists or antagonists of the PPAR receptor.
Therapeutic uses of quinoline derivatives
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, (2008/06/13)
A method for mediating the activity of PPAR-γ receptor comprising contacting said PPAR-γ receptor with a compound of formula I defined herein. Also disclosed is the treatment of a patient suffering from a physiological disorder capable of being modulated
Development of a Novel Series of (2-quinolinylmethoxy)phenyl-Containing Compounds as High-Affinity Leukotriene D4 Receptor Antagonists. 2. Effects of an Additional Phenyl Ring on Receptor Affinity
Huang, Fu-Chih,Galemmo, Robert A.,Johnson, William H.,Poli, Gregory B.,Morrissette, Matthew M.,et al.
, p. 1194 - 1200 (2007/10/02)
This series of reports describe the development of orally active, highly potent, specific antagonists of the peptidoleukotrienes containing a (2-quinolinylmethoxy)phenyl moiety.The compounds reported in this paper contain an additional phenyl ring, which
