1232397-16-8

Basic information

• Product Name: (7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(3,4,5-trimethoxy-phenyl)amine
• Synonyms: (7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(3,4,5-trimethoxy-phenyl)amine
• CAS NO: 1232397-16-8
• Molecular Weight: 376.415
• Mol File: 1232397-16-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(3,4,5-trimethoxy-phenyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: (7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(3,4,5-trimethoxy-phenyl)amine(1232397-16-8)
• EPA Substance Registry System: (7-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(3,4,5-trimethoxy-phenyl)amine(1232397-16-8)

Safety Data

• Hazardous Substances Data: 1232397-16-8(Hazardous Substances Data)

Upstream product

• 1233184-54-7 7-bromo-2-(methylsulfinyl)pyrrolo[2, 1-f][1,2,4]triazine 
• 1232815-49-4 2-thioxo-2,3-dihydro-1H-pyrrolo[2,1-f][1,2,4]triazin-4-one 
• 1318629-72-9 C₂₃H₂₂N₂O₅ 
• 1318629-69-4 N-(2-formyl-5-phenyl-1H-pyrrol-1-yl)-carbamic acid tert-butyl ester 
• 1318629-68-3 N-(2-bromo-5-formyl-1H-pyrrol-1-yl)-carbamic acid tert-butyl ester 
• 24313-88-0 3,4,5-Trimethoxyaniline 
• 1232815-55-2 2-methylsulfinyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine 
• 1232815-54-1 2-methylsulfanyl-7-phenyl-pyrrolo[2,1-f][1,2,4]triazine 
• 1232815-48-3 1-(3-benzoyl-thioureido)-1H-pyrrole-2-carboxylic acid methyl ester 
• 1233094-95-5 7-bromo-2-methylsulfanyl-pyrrolo[2,1-f][1,2,4]triazine 

Relevant articles and documents

Discovery and process synthesis of novel 2,7-pyrrolo[2,1- f ][1,2,4]triazines

The synthesis of a new kinase inhibitor template 2-anilino-7-aryl- pyrrolo[2,1-f][1,2,4]triazine is described which includes a late stage orthogonally reactive key intermediate amenable to rapid diversification as well an optimized in situ triflate displa

PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS

The present invention provides a compound of formula (I) or a salt form thereof, wherein Q1, Q2, Q3, and Q4 are as defined herein. The compound of formula (I) has ALK and/or JAK2 inhibitory activity, and may be used to treat proliferative disorders.