123240-24-4

Basic information

• Product Name: 6-Ethyl-5-(4-morpholin-4-yl-3-nitro-phenyl)-pyrimidine-2,4-diamine
• Synonyms: 6-Ethyl-5-(4-morpholin-4-yl-3-nitro-phenyl)-pyrimidine-2,4-diamine
• CAS NO: 123240-24-4
• Molecular Weight: 344.373
• Mol File: 123240-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Ethyl-5-(4-morpholin-4-yl-3-nitro-phenyl)-pyrimidine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Ethyl-5-(4-morpholin-4-yl-3-nitro-phenyl)-pyrimidine-2,4-diamine(123240-24-4)
• EPA Substance Registry System: 6-Ethyl-5-(4-morpholin-4-yl-3-nitro-phenyl)-pyrimidine-2,4-diamine(123240-24-4)

Safety Data

• Hazardous Substances Data: 123240-24-4(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 21813-35-4 2,4-diamino-5-(4-chloro-3-nitrophenyl)-6-ethylpyrimidine 

Relevant articles and documents

Structural Studies on Bioactive Compounds. 8. Synthesis, Crystal Structure, and Biological Properties of a New Series of 2,4-Diamino-5-aryl-6-ethylpyrimidine Dihydrofolate Reductase Inhibitors with in Vivo Activity against a Methotrexate-Resistant Tumor C

A series of 2,4-diamino-5-aryl-6-ethylpyrimidines embracing basic substituents in the 5-aryl ring was synthesized and evaluated for inhibitory activity against rat liver dihydrofolate reductase (DHFR).Maximal enzyme inhibition was observed for compounds b