1232402-65-1

Usage

Type of compound

Acetyl chloride The chemical is a derivative of acetyl chloride, which is a type of organic compound.

Use

Synthesis of various organic compounds The chemical is used as a reagent in the synthesis of various organic compounds by reacting with other chemicals to form new compounds.

Application

Pharmaceutical industry The chemical is commonly used in the pharmaceutical industry as an intermediate in the synthesis of drugs and active pharmaceutical ingredients.

Handling and storage

Sensitive to moisture, should be stored in a cool, dry place The chemical can react with moisture, so it must be stored in a way that prevents it from coming into contact with moisture. It should be kept in a cool, dry place to prevent it from degrading.

Hazardous if not used properly

Can be hazardous The chemical can be dangerous if not handled and stored properly, so it's important to use it with caution.

Upstream product

• 66916-99-2 2-(2-bromo-4-(methoxy)phenyl)acetic acid 

Downstream Products

• 1393822-47-3 2-(6-methoxy-1-phenyl-1H-indol-2-yl)propionic acid ethyl ester 
• 1393822-59-7 4-(2-bromo-4-methoxyphenyl)-2-methyl-buta-2,3-dienoic acid ethyl ester 

Relevant academic research and scientific papers

Palladium-catalyzed tandem allenyl and aryl C-N bond formation: Efficient access to N-functionalized multisubstituted indoles

An efficient palladium-catalyzed synthesis of N-functionalized multisubstituted indoles from easily accessible ortho-haloarylallenes and primary amines has been developed. A wide range of electronically and structurally varied nitrogen fragments could be introduced through this tandem C-N bond-forming process by tuning the reaction conditions.

Design, synthesis, and pharmacological evaluation of a novel series of hormone sensitive lipase inhibitor

HSL inhibition is a promising approach to the treatment of dyslipidemia. As a result of re-optimization of lead compound 2, we identified novel compound 25a exhibiting potent inhibitory activity against HSL enzyme and cell with high selectivity for cholin

Copper(II)-catalyzed meta-selective direct arylation of α-aryl carbonyl compounds

Strong competition: A method for the meta-selective arylation of the highly versatile α-aryl carbonyl motif using diaryliodonium salts is described. In this CuII-catalyzed process the remote carbonyl group is capable of overpowering even strongly para-directing functionalities to form the elusive meta-products (see scheme). Remarkably, the arylation process can also operate under metal-free conditions.