66916-99-2

Basic information

• Product Name: 2-Bromo-4-methoxyphenylacetic acid
• Synonyms: 2-BROMO-4-METHOXYPHENYLACETIC ACID;2-(2-BroMo-4-Methoxyphenyl)-acetic acid;2-broMo-4-Methoxyphenylacetci acid;2-BroMo-4-Methoxyphenylacetic acid 97%;Benzeneacetic acid,2-bromo-4-methoxy-
• CAS NO: 66916-99-2
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.07
• Product Categories: Aromatic Phenylacetic Acids and Derivatives;Phenylacetic acid;C9;Carbonyl Compounds;Carboxylic Acids
• Mol File: 66916-99-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 127-131 °C(lit.)
• Boiling Point: 353.6 °C at 760 mmHg
• Flash Point: 167.6 °C
• Appearance: /
• Density: 1.56 g/cm³
• Vapor Pressure: 1.31E-05mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 4.20±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-4-methoxyphenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-methoxyphenylacetic acid(66916-99-2)
• EPA Substance Registry System: 2-Bromo-4-methoxyphenylacetic acid(66916-99-2)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-50
• Safety Statements: 60-61
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 2
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 66916-99-2(Hazardous Substances Data)

Usage

Chemical Properties

Solid

InChI:InChI=1/C9H9BrO3/c1-13-7-3-2-6(4-9(11)12)8(10)5-7/h2-3,5H,4H2,1H3,(H,11,12)

Upstream product

• 198630-93-2 methyl 2-(2-bromo-4-methoxyphenyl)acetate 
• 54788-18-0 2-bromo-1-(bromomethyl)-4-methoxybenzene 
• 36942-56-0 3-bromo-4-methylanisole 
• 66916-98-1 2-(2-bromo-4-methoxyphenyl)acetonitrile 

Downstream Products

• 88491-44-5 2-(2-bromo-4-hydroxyphenyl)acetic acid 
• 1380068-76-7 2-[2-bromo-4-(cyclopropylmethoxy)phenyl]-1-(5-{[tris(1-methylethyl)silyl]oxy}pyridin-2-yl)ethanol 
• 1380069-58-8 1-[2-bromo-4-(cyclopropylmethoxy)phenyl]propan-2-one 
• 1380070-11-0 2-(2-bromo-4-hydroxyphenyl)-N-methoxy-N-methylacetamide 
• 1380070-12-1 2-(2-bromo-4-(methoxymethoxy)phenyl)-N-methoxy-N-methylacetamide 
• 1380070-13-2 1-(2-bromo-4-(methoxymethoxy)phenyl)propan-2-one 
• 1380070-14-3 1-(2-bromo-4-(methoxymethoxy)phenyl)-2-(5-(triisopropylsilyloxy)pyridin-2-yl)propan-2-ol 
• 1644247-57-3 methyl 2-acetoxy-2-(2-bromo-4-methoxyphenyl)acetate 
• 1644247-67-5 methyl 2-(2-bromo-4-methoxyphenyl)-2-(phenylthio)acetate 
• 1644247-45-9 methyl 2-(2-bromo-4-methoxyphenyl)-2-diazoacetate 
• 1334783-14-0 5-methoxy-2-(2-{2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl}-2-oxoethyl)benzonitrile 

Relevant articles and documents

Copper-Catalyzed Lactamization of (E)-2-(2-Bromophenyl)-3-arylacrylamides for the Synthesis of (E)-3-Arylideneindolin-2-ones

A copper-catalyzed, ligand-free intramolecular C-N coupling of (E)-2-(2-bromophenyl)-3-arylacrylamides has been developed. This protocol provides an efficient and practical synthetic route for the biologically important (E)-3-arylideneindolin-2-ones from

Regioselective aryl radical cyclisation. Part 2. Synthesis of octahydro-1H-dibenzo[a,d]cycloheptenes through 7-endo ring closure

A simple convergent synthesis of trans- and cis-octahydro-1H-dibenzo[a,d]cycloheptenes 15a-c and 16a-c and 20a-c and 21a-c through implementation of a regioselective 7-endo-trig-aryl radical cyclisation of the respective 2-(o-bromoarylethyl)-1-methylenecy