1232407-18-9

Basic information

• Product Name: 2-bromo-N,3-dimethoxy-N-methylbenzamide
• Synonyms: 2-bromo-N,3-dimethoxy-N-methylbenzamide
• CAS NO: 1232407-18-9
• Molecular Weight: 274.114
• Mol File: 1232407-18-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-bromo-N,3-dimethoxy-N-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N,3-dimethoxy-N-methylbenzamide(1232407-18-9)
• EPA Substance Registry System: 2-bromo-N,3-dimethoxy-N-methylbenzamide(1232407-18-9)

Safety Data

• Hazardous Substances Data: 1232407-18-9(Hazardous Substances Data)

Upstream product

• 88377-29-1 2-bromo-3-methoxybenzoic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 586-38-9 3-Methoxybenzoic acid 
• 1711-05-3 m-anisoyl chloride 
• 152121-82-9 N,3‐dimethoxy‐N‐methylbenzamide 

Downstream Products

• 1232407-19-0 1-(2-bromo-3-methoxyphenyl)ethanone 
• 1232407-21-4 1-[2-bromo-3-(difluoromethoxy)phenyl]ethanone 
• 1232835-02-7 1-(2-Bromo-3-ethoxy phenyl)ethanone 
• 1232407-20-3 1-(2-bromo-3-hydroxy phenyl)ethanone 

Relevant articles and documents

Palladium-Catalyzed, ortho-Selective C-H Halogenation of Benzyl Nitriles, Aryl Weinreb Amides, and Anilides

A palladium-catalyzed, ortho-selective C-H halogenation methodology is reported herein. The highlight of the work is the highly selective C(sp2)-H functionalization of benzyl nitriles in the presence of activated C(sp3)-H bond, which results in good yields of the halogenated products with excellent regioselectivity. Along with benzyl nitriles, aryl Weinreb amides and anilides have been evaluated for the transformation using aprotic conditions. Mechanistic studies yield interesting aspects with respect to the pathway of the reaction and the directing group abilities.