1232829-94-5

Upstream product

• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 89794-02-5 4-bromo-2-chlorotoluene 
• 132635-95-1 5-(S)-<3.3.0>-1-aza-2-thia-3-oxabicyclooctane-2,2-dioxide 

Relevant academic research and scientific papers

Discovery and optimisation of 1-acyl-2-benzylpyrrolidines as potent dual orexin receptor antagonists

Starting from a thienopiperidine lead compound with high intrinsic clearance in rat and human liver microsomes and low aqueous solubility, a novel series of 1-acyl-2-benzylpyrrolidines were discovered as potent and competitive dual orexin receptor antagon

CYCLIC AMINE COMPOUNDS

Problems to be solved are to provide novel low-molecular compounds which exhibit calcium receptor antagonist activity, and which are highly safe and orally administrable. As a means for solving the problems, compounds having the Formula (I) or pharmaceuti