1233477-62-7Relevant academic research and scientific papers
A Concise Synthesis of (2R,3R)- and (2R,3S)-3-Hydroxypipecolic Acids, and Total Synthesis of (-)-Deoxoprosopinine and (+)-2-epi-Deoxoprosopinine from D -Glycals
Mallick, Asadulla,Kumari, Nitee,Roy, Rashmi,Palanivel, Ashokkumar,Vankar, Yashwant D.
, p. 5557 - 5563 (2014/10/15)
Short and efficient formal syntheses of (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids, and total syntheses of (-)-deoxoprosopinine and (+)-2-epi-deoxoprosopinine have been achieved starting from D-glycals. The key steps involved in these syntheses were Ferrier rearrangement, azide reduction, intramolecular cyclization, and Grignard reaction. New syntheses of (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids, and total syntheses of (-)-deoxoprosopinine and (+)-2-epi-deoxoprosopinine are reported. The syntheses started from D-glycals, and Ferrier rearrangement, intramolecular cyclization, and Grignard reactions.
Synthesis of (-)-deoxoprosophylline, (+)-2- epi -deoxoprosopinine, and (2 R,3 R)- and (2 R,3 S)-3-hydroxypipecolic acids from d -glycals
Kokatla, Hari Prasad,Lahiri, Rima,Kancharla, Pavan K.,Doddi, Venkata Ramana,Vankar, Yashwant D.
supporting information; experimental part, p. 4608 - 4611 (2010/09/30)
(Figure presented) New syntheses of (-)-deoxoprosophylline, (+)-2-epi-deoxoprosopinine, and (2R,3R)- and (2R,3S)-3-hydroxypipecolic acids are reported. Utilization of the chiral functionalities of Perlin aldehydes, derived from 3,4,6-tri-O-benzyl glycals,
