123348-79-8Relevant academic research and scientific papers
CONVENIENT ROUTES TO ALKYL-SUBSTITUTED POLYAMINES
Golding, Bernard T.,O"Sullivan, Mary C.,Smith, Lewis L.
, p. 6651 - 6654 (1988)
Alkyl-substituted polyamines, valuable for biological studies, can be prepared from N-phenylmethoxycarbonyl-1,4-diaminobutane (1b) and N-phenylmethoxycarbonyl-4-azidobutanamine (4a) by utilising the following reactions: (i) reduction of the phenylmethoxycarbonyl group to methyl by borane and (ii) combination of the Staudinger and aza-Wittig reactions .
Urea derivatives and pharmaceutical compositions thereof
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, (2008/06/13)
Objects of the present invention are to create compounds having urea structure as basic structure and having a sulfur atom and an amide bond in side chains and to find pharmacological effects thereof, particularly TNF-α production inhibitory effects. The
