1233495-36-7Relevant academic research and scientific papers
A domino reaction of α,β-acetylenic λ-hydroxy nitriles with arenecarboxylic acids: An unexpected facile shortcut to 4-cyano-3(2 H)-furanones
Trofimov, Boris A.,Shemyakina, Olesya A.,Malkina, Anastasiya G.,Ushakov, Igor A.,Kazheva, Olga N.,Alexandrov, Grigorii G.,Dyachenko, Oleg A.
, p. 3200 - 3203 (2010)
(Figure Presented) An unexpected facile domino reaction of α,β-acetylenic λ-hydroxy nitriles with arenecarboxylic acids (Et3N, MeCN, 20-25 °C, 48 h) affords 4-cyano-3(2H)-furanones in 67-86% yield. The reaction is triggered by the addition of a
