1233702-33-4

Upstream product

• 202872-01-3 diethyl 2-(3-oxo-3-phenylpropyl)-2-(prop-2-yn-1-yl)malonate 
• 17920-23-9 diethyl propargylmalonate 
• 105-53-3 diethyl malonate 

Relevant academic research and scientific papers

Cyclization of alk-5-ynyl ketones promoted by Tf2NH and In(OTf)3: selective synthesis of 5- and 7-membered carbocycles

Combined use of Tf2NH and In(OTf)3effectively promotes the cyclization of alk-5-ynyl ketones to cyclopent-1-enyl ketones at 30?°C. Single use of Tf2NH or In(OTf)3requires heating at 50?°C for efficient cyclizati

Gold-catalysed room-temperature cycloisomerisation of alkynes and unactivated enolisable ketones

The cycloisomerisation of simple keto-alkynes proceeds at room temperature under the mild conditions of gold catalysis. Bicyclic fused and spiro compounds can be obtained by overall 5-exo and 6-exo carbon-carbon bond-forming cyclisations.