1233703-80-4Relevant academic research and scientific papers
Stereoselective conjugate addition of carbonyl compounds to maleimides using a diaminomethyleneindenedione organocatalyst
Nakashima, Kosuke,Kawada, Masahiro,Hirashima, Shin-ichi,Kosugi, Ayako,Kato, Mana,Yoshida, Akihiro,Koseki, Yuji,Miura, Tsuyoshi
, p. 888 - 895 (2016/09/02)
A diaminomethyleneindenedione motif can serve as an excellent double hydrogen bonding donor. Bifunctional chiral primary amine 3 bearing a diaminomethyleneindenedione motif is an excellent organocatalyst to promote the asymmetric conjugate additions of va
Asymmetric conjugate addition of ketones to maleimides using diaminomethyleneindenedione organocatalyst
Nakashima, Kosuke,Kawada, Masahiro,Hirashima, Shin-Ichi,Kato, Mana,Koseki, Yuji,Miura, Tsuyoshi
, p. 1248 - 1252 (2015/03/31)
Abstract A novel diaminomethyleneindenedione (DMI) organocatalyst efficiently promotes the asymmetric conjugate addition of a ketone to a maleimide to afford the corresponding addition product in a high yield with up to 99% enantiomeric excess.
Enantioselective Michael addition of ketones to maleimides catalyzed by bifunctional monosulfonyl DPEN salt
Yu, Feng,Sun, Xiaomin,Jin, Zhichao,Wen, Shigang,Liang, Xinmiao,Ye, Jinxing
supporting information; experimental part, p. 4589 - 4591 (2010/11/18)
An unprecedented enantioselective Michael addition of various ketones to maleimides catalyzed by a simple bifunctional primary amine, monosulfonyl DPEN salt, is reported and provides the desired adducts in good to excellent yields (up to 99%) with excellent enantioselectivities (up to 99%).
