1233717-68-4 Usage
Uses
Used in Pharmaceutical Industry:
Bis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(0), Pd 16.7%, is used as a catalyst for cross-coupling reactions in the synthesis of complex organic molecules, including pharmaceutical compounds. Its high purity and palladium content contribute to the efficient formation of desired products, reducing side reactions and improving overall yields.
Used in Chemical Industry:
In the chemical industry, Bis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(0), Pd 16.7%, is used as a catalyst for sp2-sp3 coupling reactions, including Suzuki, Negishi-type, Heck, Sonogashira, and Buchwald-Hartwig coupling reactions. These reactions are essential for the synthesis of various organic compounds, such as polymers, dyes, and specialty chemicals.
Used in Research and Development:
Bis[di-tert-butyl(4-dimethylaminophenyl)phosphine]palladium(0), Pd 16.7%, is utilized in research and development settings for the investigation of new cross-coupling reactions and the optimization of existing ones. Its high purity and palladium content make it an ideal catalyst for exploring novel synthetic routes and improving reaction conditions.
Reaction
Catalyst used for the Heck alkynylation of aryl and heteroaryl chlorides.
Check Digit Verification of cas no
The CAS Registry Mumber 1233717-68-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,3,7,1 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1233717-68:
(9*1)+(8*2)+(7*3)+(6*3)+(5*7)+(4*1)+(3*7)+(2*6)+(1*8)=144
144 % 10 = 4
So 1233717-68-4 is a valid CAS Registry Number.
1233717-68-4Relevant academic research and scientific papers
The impact of palladium(II) Reduction pathways on the structure and activity of palladium(0) catalysts
Wei, Carolyn S.,Davies, Geraint H. M.,Soltani, Omid,Albrecht, Jacob,Gao, Qi,Pathirana, Charles,Hsiao, Yi,Tummala, Srinivas,Eastgate, Martin D.
, p. 5822 - 5826 (2013/07/11)
Two roads diverged: The mechanism of insitu PdII catalyst activation to generate an active {LnPd0} catalyst from an air-stable PdII precursor was examined using the standard conditions of a Miyaura borylation reaction. Two pathways for catalyst activation exist under these conditions, producing two structurally and chemically distinct {LnPd0} complexes (see scheme). Copyright
