1233731-05-9Relevant academic research and scientific papers
Ru(III)-catalyzed oxidative reaction in ionic liquid: An efficient and practical route to 2-substituted benzothiazoles and their hybrids with pyrimidine nucleoside
Fan, Xuesen,Wang, Yangyang,He, Yan,Zhang, Xinying,Wang, Jianji
experimental part, p. 3493 - 3496 (2010/08/20)
An efficient, practical and environmentally benign synthesis of 2-substituted benzothiazoles was developed through RuCl3-catalyzed oxidative condensation of 2-aminothiophenol with aldehyde in ionic liquid by using air as the oxidant. With this procedure, a series of 2-substituted benzothiazoles and benzothiazole/pyrimidine nucleoside hybrids with antimicrobial activities were efficiently prepared from easily accessible starting materials.
