123387-56-4Relevant academic research and scientific papers
α-Lithioamine Synthetic Equivalents: Syntheses of Diastereoisomers from the Boc Piperidines
Beak, Peter,Lee, Won Koo
, p. 2578 - 2580 (2007/10/02)
The α'-lithiations and electrophilic substitutions of selected Boc piperidines provide single or separable diastereoisomeric 2-substituted, 2,4-disubstituted, and 2,4,6-trisubstituted Boc piperidines which are readily hydrolyzed to the substituted piperidines.
α-LITHIOAMINE SYNTHETIC EQUIVALENTS FROM DIPOLE-STABILIZED CARBANIONS: THE t-BOC GROUP AS AN ACTIVATOR FOR α'-LITHIATION OF CARBAMATES
Beak, Peter,Lee, Won-Koo
, p. 1197 - 1200 (2007/10/02)
The t-Boc group activates the α'-lithiation of piperidinyl and related carbamates to give lithium reagents which add to electrophiles to provide α'-elaborated carbamates.
