1233947-49-3

Upstream product

• 3767-28-0 4-nitrophenyl-α-D-glucopyranoside 
• 108-30-5 succinic acid anhydride 
• 59862-97-4 p-aminophenyl-2,3,4,6-tetra-O-acetyl-α-D-glucopyranoside 
• 14131-42-1 p-nitrophenyl 2,3,4,6-tetra-O-acetyl-α-D-glucopyranoside 

Downstream Products

• 1303982-39-9 C₃₄H₄₀N₄O₁₂ 
• 1303982-27-5 C₃₄H₄₀N₄O₁₁ 
• 1303982-35-5 C₃₄H₄₀N₄O₁₁ 
• 1303982-33-3 C₃₆H₄₁N₅O₁₁ 
• 1303982-37-7 C₃₆H₄₁N₅O₁₁ 
• 1303982-23-1 C₃₄H₄₀N₄O₁₀ 
• 1303982-25-3 C₃₆H₄₁N₅O₁₀ 
• 1303982-29-7 C₃₆H₄₁N₅O₁₀ 
• 1303982-31-1 C₃₈H₄₂N₆O₁₀ 

Relevant academic research and scientific papers

Selective α-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties

We constructed a library of sugar-dipeptide conjugate to find out the best complementary against hydrophobic pocket of α-glucosidase. The best substrate showed 150-fold improved Km value relative p-acetaminophenyl-α-d-glucopyranoside for α-glucosidase from Bacillus stearothermophillus. Using information from the complementary, we synthesized sp-WY and β-Glc-sp-WY, which selectivity inhibited the cognate enzyme.