123438-77-7Relevant academic research and scientific papers
An efficient route to a 5,6-dihydropyrano[3,4-b]pyridin-8-one core in two steps from enaminolactones
Sall, Cheikh,Desbois, Nicolas,Paquelet, Sandrine,Camacho, José R.,Chezal, Jean Michel,Teulade, Jean-Claude,Blache, Yves
, p. 1301 - 1304 (2008/09/18)
A convenient two step conversion of heterocyclic enaminolactones to heterocyclic fused 2-pyran-1-ones is reported. The use of this method can be applied to a wide variety of aromatic and heteroaromatic amines to give potentially biologically active compounds in good yields.
A solvent-free synthesis of β-amino-α,β-unsaturated ketones and esters catalysed by sulfated zirconia
Zhang, Zhan-Hui,Song, Li-Ming
, p. 817 - 820 (2007/10/03)
β-Amino-α,β-unsaturated ketones and esters are synthesised by the condensation of β-dicarbonyl compounds with amines in the presence of a solid superacid sulfated zirconia (SO42-/ZrO 2, SZ) under solvent-free conditions.
Enaminones as potential prodrugs of primary and secondary amines
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, (2008/06/13)
Novel enzymatically labile enaminones useful as potential prodrugs of primary and secondary amines are disclosed. Also, disclosed herein are compositions comprising said amines and methods of administering said composition to warm-blooded animals.
