123444-70-2

Upstream product

• 75-24-1 trimethylaluminum 
• 80183-15-9 (2R,3R)-1,4-bis(benzyloxy)-2,3-epoxy butane 
• 123444-69-9 (2S)-tert-butyl(2-methylpent-4-ynyloxy)diphenylsilane 
• 136262-53-8 (3S)-4-[(tert-butyldiphenylsilyl)oxy]-3-methylbutanenitrile 
• 123444-68-8 (S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutanal 
• 123444-67-7 (R)-3-[(tert-butyl)diphenylsilyloxy]-1-iodo-2-methylpropane 

Downstream Products

• 123465-13-4 (E)-(3S,7S,8S)-2-Benzenesulfonyl-8,9-bis-benzyloxy-7-benzyloxymethyl-1-[(2S,3S,5R,6S)-3-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-5-methyl-tetrahydro-pyran-2-yl]-3,5-dimethyl-non-5-en-1-one 
• 123444-72-4 (E)-(3S,7S,8S)-8,9-Bis-benzyloxy-7-benzyloxymethyl-1-[(2S,3S,5R,6S)-3-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-5-methyl-tetrahydro-pyran-2-yl]-3,5-dimethyl-non-5-en-1-one 
• 123444-73-5 (E)-(3S,7S,8S)-8,9-Bis-benzyloxy-7-benzyloxymethyl-1-((2S,3S,5R,6S)-3-hydroxy-6-methoxy-5-methyl-tetrahydro-pyran-2-yl)-3,5-dimethyl-non-5-en-1-one 
• 123444-74-6 (2R,3S,5R,6S)-2-((E)-(1S,3S,7S,8S)-8,9-Bis-benzyloxy-7-benzyloxymethyl-1-methoxy-3,5-dimethyl-non-5-enyl)-3,6-dimethoxy-5-methyl-tetrahydro-pyran 
• 123444-71-3 C₃₈H₄₄O₅S 

Relevant academic research and scientific papers

AN ENANTIOSELECTIVE SYNTHESIS OF THE C(10) TO C(23) BACKBONE OF THE POTENT IMMUNOSUPPRESSANT FK506

The C(10) to C(23) fragment of FK506 has been pepared in a convergent, highly stereocontrolled, fashion.The key transformations entailed opening of a symmetrical trans-disubstituted epoxide with a trisubstituted vinylalane ate complex, the reductive remov