80183-15-9

Usage

Uses

Used in Pharmaceutical Industry:
(2R,3R)-2,3-bis(benzyloxyMethyl)oxirane is used as an intermediate in the synthesis of various pharmaceuticals for its ability to undergo various chemical reactions to form other compounds.
Used in Agrochemical Industry:
(2R,3R)-2,3-bis(benzyloxyMethyl)oxirane is used as an intermediate in the production of agrochemicals for its versatility in forming other compounds.
Used in Organic Synthesis:
(2R,3R)-2,3-bis(benzyloxyMethyl)oxirane is used as a protective group for alcohols in organic synthesis due to its stability and ease of manipulation in chemical reactions.

Upstream product

• 68972-93-0 (E)-1,4-bis(benzyloxy)-2-butene 
• 80109-49-5 1,4-bis-O-(benzyloxy)-2-chloro-2-deoxy-D-erythritol formate 
• 100-44-7 benzyl chloride 
• 80109-48-4 1,4-bis-O-(benzyloxy)-D-threitol cyclic ethyl orthoformate 
• 100-39-0 benzyl bromide 
• 210104-38-4 (S)-3-((1R,2S)-3-Benzyloxy-1-benzyloxymethyl-2-hydroxy-propoxy)-5-phenyl-pent-4-ynethioic acid S-tert-butyl ester 
• 195374-95-9 (2S,4R,5S)-4,5-Bis-benzyloxymethyl-2-phenylethynyl-[1,3]dioxolane 
• 69010-01-1 (2R*,3S*)-1,4-bis(benzyloxy)butane-2,3-diol 
• 100-51-6 benzyl alcohol 

Downstream Products

• 200636-15-3 (2R,3S)-1,4-dibenzyloxy-3-(3-hydroxypropoxy)butan-2-ol 
• 1101134-42-2 C₂₁H₂₆O₃ 
• 95532-11-9 (2S,3S)-1,4-bis(benzyloxy)-3-methylbutan-2-ol 
• 134964-82-2 1-((2R,3R)-2,3-Bis-benzyloxymethyl-aziridin-1-yl)-propan-1-one 
• 200636-22-2 (2R,3S)-1,4-dibenzyloxy-3-(3-pivaloyloxypropoxy)butan-2-ol 
• 192863-92-6 (2S,3S)-1-Benzyloxy-3-benzyloxymethyl-pent-4-en-2-ol 
• 123444-70-2 (E)-(2S,3S,7S)-1-Benzyloxy-3-benzyloxymethyl-8-(tert-butyl-diphenyl-silanyloxy)-5,7-dimethyl-oct-4-en-2-ol 
• 1271145-22-2 (2R*,3S*)-2,3-bis(benzyloxymethyl)-1,4-dioxane 
• 136258-99-6 (2R,3S)-1,4-Bis-benzyloxy-3-iodo-butan-2-ol 

Relevant academic research and scientific papers

PROCESSES FOR THE PREPARATION OF ARGINASE INHIBITORS AND THEIR SYNTHETIC INTERMEDIATES

Provided herein are processes and intermediates useful for the preparation of certain compounds, including a compound of formula 21 or formula 22 or a pharmaceutically acceptable salt of either.

The synthesis of the 2, 3-difluorobutan-1, 4-diol diastereomers

The diastereoselective synthesis of fluorinated building blocks that contain chiral fluorine substituents is of interest. Here we describe optimisation efforts in the synthesis of anti-2, 3-difluorobutane-1, 4-diol, as well as the synthesis of the corresponding syn-diastereomer. Both targets were synthesised using an epoxide opening strategy.

Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from (Z)-but-2-ene-1,4-diol or but-2-yne-1,4-diol

3,4-Ethylenedioxythiophene (EDOT) was synthesized from commercially available (Z)-but-2-ene-1,4-diol or but-2-yne-1,4-diol using epoxidation, etherification, and thiophene formation. The Japan Institute of Heterocyclic Chemistry.

Deracemization of anti-1,2-diols leading to trans-epoxides via oxazaborolidine-mediated enantiomer-differentiating ring-cleavage of acetal derivatives

An enantioconvergent transformation of racemic anti-1,2-diols to enantiomerically enriched (71-96% ee) trans-epoxides is realized via chiral oxazaborolidine-mediated enantiomer-differentiating ring-cleavage reaction of the acetal derivatives.

Total Synthesis of Ionophore Antibiotic X-14547A

A highly stereocontrolled and convergent total synthesis of optically active ionophore antibiotic X-14547A (1) was designed and carried out.Degradative reactions led to the key intermediates 3 and 6, which served as convenient comparison stages.The tetrah