1234616-02-4

Usage

Chemical structure

Substituted naphthalene derivative with chlorine and iodine atoms attached to the 1 and 4 positions, respectively, and a diazanaphthalene ring system.

Type of compound

Heterocyclic, aromatic compound

Applications

a. Intermediate in the synthesis of various pharmaceuticals and organic chemicals
b. Utilized in research and experimental studies due to its unique structure and reactivity

Hazards

May pose hazards to human health and the environment

Handling and disposal

Requires proper handling and disposal procedures to minimize potential risks

Upstream product

• 33402-75-4 4-methylnicotinic acid methyl ester 
• 959558-50-0 4-iodine-2,7-naphthyridine-1(2H)-one 
• 67988-50-5 2,7-naphthyridinyl-1(2H)-one 

Relevant academic research and scientific papers

Pyrido/pyridazocyclic compound and application thereof

The invention discloses a pyrido/pyridazocyclic compound, a pharmaceutically acceptable salt and a solvent compound thereof. The invention further provides a preparation method of the compound, a composition with the compound and application of the compound for preparing medicines for treating diseases or disorders related to EED (embryonic ectoderm development) protein and/or PRC2 (polycomb repressive complex 2) protein composition action mechanisms.

Preparation of Polyfunctional Naphthyridines by Cobalt-Catalyzed Cross-Couplings of Halogenated Naphthyridines with Magnesium and Zinc Organometallics

CoCl2 (5%) catalyzes cross-couplings of various halogenated naphthyridines with alkyl- and arylmagnesium halides. Also, arylzinc halides undergo smooth cross-couplings with various naphthyridines in the presence of CoCl2·2LiCl (5%) a