1234619-69-2

Upstream product

• 170572-49-3 2-fluoro-4-cyanotoluene 
• 1161921-91-0 4-methyl-3-(methylsulfonyl)benzonitrile 
• 1161921-93-2 4-formyl-3-(methylsulfonyl)benzonitrile 
• 1161921-92-1 4-[2-(dimethylamino)vinyl]-3-(methylsulfonyl)benzonitrile 
• 1234620-64-4 (rac)-2-amino-7-[4-cyano-2-(methylsulfonyl)phenyl]-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile 
• 1234620-66-6 (rac)-7-[4-cyano-2-(methylsulfonyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-methyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile 
• 1234619-35-2 (rac)-7-[4-cyano-2-(methylsulfonyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-5-methyl-4-[3-(trifluoromethyl)phenyl]-4,7-dihydro[1,2,4]triazolo-[1,5-a]pyrimidine-6-carbonitrile 
• 1234620-63-3 4-(2-cyano-3-oxobut-1-en-1-yl)-3-(methylsulfonyl)benzonitrile 
• 1234620-65-5 rac-4-[2-cyano-1-(3,5-diamino-1H-1,2,4-triazol-1-yl)-3-oxobutyl]-3-(methylsulfonyl)benzonitrile 
• 1234619-38-5 (rac)-2-Amino-7-[4-cyano-2-(methylsulfonyl)phenyl]-5-methyl-4-[3-(trifluoromethyl)phenyl]-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile 
• 79-22-1 methyl chloroformate 

Relevant academic research and scientific papers

TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD

The present invention relates to novel heterocyclically fused diaryldihydropyrimidine derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.