1234673-35-8Relevant academic research and scientific papers
Cysteine-based mannoside glycoclusters: Synthetic routes and antiadhesive properties
Schierholt, Alexander,Hartmann, Mirja,Schwekendiek, Kirsten,Lindhorst, Thisbe K.
experimental part, p. 3120 - 3128 (2010/08/19)
Clustermannosides of different valency were synthesised based on cysteine. By employing the orthogonally protected amino acid as scaffold molecule, a variety of structurally varied products can be obtained according to different synthetic routes. Testing of the prepared glycoclusters as inhibitors of type 1 fimbriae mediated bacterial adhesion is reported, giving hints about the influence of sugar valency, sugar scaffolding, and the nature of the glycosidic aglycon in this testing system.
