1234703-91-3Relevant academic research and scientific papers
Efficient synthesis of β-oxoalkyl carbamates from carbon dioxide, internal propargylic alcohols, and secondary amines catalyzed by silver salts and DBU
Qi, Chaorong,Huang, Liangbin,Jiang, Huanfeng
experimental part, p. 1433 - 1440 (2010/10/20)
The three-component reaction of internal propargylic alcohols with secondary amines and carbon dioxide proceeded smoothly in the presence of a catalyst system comprising a silver salt and 1,8-diazabicyclo[5.4.0]undec-7-ene in 1,4-dioxane at 90 °C to give the corresponding β-oxoalkyl carbamates in good to high yields. The counterion of the silver salt had little effect on the reaction whereas the nature of the organic base had a marked influence. Georg Thieme Verlag Stuttgart.
