1234714-93-2Relevant academic research and scientific papers
Gold-catalyzed three-component coupling: Oxidative oxyarylation of alkenes
Melhado, Asa D.,Brenzovich Jr., William E.,Lackner, Aaron D.,Toste, F. Dean
supporting information; experimental part, p. 8885 - 8887 (2010/08/21)
The three-component coupling of terminal alkenes with arylboronic acids and oxygen nucleophiles is described. The reaction employs a binuclear gold(I) bromide as a catalyst and Selectfluor reagent as the stoichiometric oxidant. Alcohols, carboxylic acids, and water can be employed as oxygen nucleophiles, thus providing an efficient entry into β-aryl ethers, esters, and alcohols from alkenes.
