123474-60-2Relevant academic research and scientific papers
The Total Synthesis of Agglomerin A and (+/-)-Carolinic Acid. A General Method for the Preparation of 3-Acyl Tetronic Acids Via Direct Acylation of O-Methyl 3-Stannyl Tetronates
Ley, Steven V.,Trudell, Mark L.,Wadsworth, David J.
, p. 8285 - 8296 (1991)
A variety of O-methyl-3-acyl tetronates were prepared in good yield from the corresponding acid chlorides via a palladium catalyzed acylation of O-methyl 3-(tri-n-butylstannyl) tetronate 5.This new synthetic method was the exploited for the total synthesis of the novel antibiotic agglomerin A 3a, as well as the fungal metabolite (+/-)-carolinic acid 15.
